Enzymes

Description: Streptavidin : Alkaline Phosphatase

Description: Sirtuin 1 (193-741) active enzyme. Sirtuin 1 is a NAD-dependent deacetylase, which regulates process ... more

Description: Sirtuin 1 (193-741) active enzyme. Sirtuin 1 is a NAD-dependent deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Deacetylates Lys-382 of p53/TP53 and impairs its ability to induce proapoptotic program and modulate cell senescence. Deacetylates TAF1B and thereby represses rDNA transcription by the RNA polymerase I. Involved in HES1- and HEY2-mediated transcriptional repression. Inhibits skeletal muscle differentiation by deacetylating PCAF and MYOD1. May serve as a sensor of the cytosolic ratio of NAD(+)/NADH, which is essential in skeletal muscle cell differentiation. Despite some ability to deacetylate histones in vitro, such activity is either weak or inexistent in vivo. Inhibited by nicotinamide. Activated by resveratrol (3,5,4-trihydroxy-trans-stilbene), butein (3,4,2,4- tetrahydroxychalcone), piceatannol (3,5,3,4-tetrahydroxy-trans-stilbene),Isoliquiritigenin(4,2,4-trihydroxychalcone), fisetin (3,7,3,4-tetrahydroxyflavone) and quercetin (3,5,7,3,4- pentahydroxyfla.Ivone). 3   collapse

Description: Protein Disulfide Isomerase Human Recombinant produced in E.coli is single, non-glycosylated, polype ... more

Description: Protein Disulfide Isomerase Human Recombinant produced in E.coli is single, non-glycosylated, polypeptide chain containing 508 amino acids and having molecular mass of 57116 Dalton. The PDI contains N-terminal 6xHis-tag and purified by proprietary chromatographic techniques.   collapse

Description: Staphylokinase Recombinant produced in E.coli is non-glycosylated polypeptide chain containing 136 a ... more

Description: Staphylokinase Recombinant produced in E.coli is non-glycosylated polypeptide chain containing 136 amino acids and having molecular weight of 15.5 kd.The Staphylokinase is purified by proprietary chromatographic techniques.   collapse

Description: Ubiquitin-Conjugating Enzyme E2I Human Recombinant produced in E.coli is single, non-glycosylated po ... more

Description: Ubiquitin-Conjugating Enzyme E2I Human Recombinant produced in E.coli is single, non-glycosylated polypeptide chain containing 154 amino acids having molecular mass of 17.9 kDa.   collapse