TLR4 Antibody

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. The calculated molecular weightsf three TLR4 isoforms are 96, 91, and 73 kDa.

  • Product Detail
  • All Images
Category Antibodies
Publication 21
Application ELISA, IHC, WB
Host Rabbit
Reactivity Human, mouse, rat, bovine
Clonality Polyclonal
Purification Antigen affinity purification
immunogen TLR4 fusion protein ag13841
Form PBS with 0.02% sodium azide and 50% glycerol pH 7.3 .
Storage Store at -20°C. Aliquoting is unnecessary for -20°C storage.
Supplier Proteintech
Isotype IgG
MW 839aa,96 kDa
Dilution WB : 1:500-1:5000IHC : 1:100-1:400
Catalog Number 19811-1-AP
Alternative Names ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Size 150ul
Gene Symbol TLR4