Calbindin Antibody

Calcium-binding proteins of different subfamilies regulate the second messenger calcium. Calbindin, calmodulin, S-100, parvalbumin and troponin C are members of the low molecular weight calcium-binding protein family (1). Calbindin is expressed in discrete neuronal populations within the CNS and is thought to act as an intracellular calcium buffering protein. Most Purkinje cells express calbindin, which is expressed when neurons start to migrate and differentiate. In contrast, other calcium buffering proteins, such as parvalbumin, are expressed later during development and in parallel with increasing neuronal activity (2).

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Category Category: Primary Antibodies
Publication 0
Application Western Blotting,Immunohistochemistry (Paraffin),Immunofluorescence (Frozen)
Specificity Calbindin Antibody detects endogenous levels of total calbindin protein.
Host Rabbit
Reactivity Human, Mouse, Rat, D. melanogaster
Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding amino acid 200 of human calbindin. Antibodies are purified by protein A and peptide affinity chromatography.
Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100
Supplier Cell Signaling Technology
MW 28
Dilution 1:1000,1:200,1:200
Catalog Number 2136
ELISA Sensitivity Endogenous