Caspase-3 Antibody

Abbiotec's Caspase-3 Antibody is a Rabbit Polyclonal antibody. The Caspase-3 Antibody was generated using Sca-1, CASP3, CPP32, caspase 3, apoptosis-related cysteine peptidase, Caspase-3, CPP32B as the antigen and it reacts with Rat, Mouse, Human. This antibody has been shown to work in applications such as: Immunohistochemistry, Western Blot, ELISA, Immunoprecipitation. Caspase-3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, Caspase-3 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-:-Gly-217 bond as well as cleaving and activating the sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. In addition Caspase-3 cleaves and activates caspase-6, -7, -9

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Category Antibodies
Publication 0
Application ELISA, IHC, IP, WB
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Caspase-3
Supplier Abbiotec
Isotype Ig
Catalog Number 250573
Conjugation Unconjugated
Size 0.1 mg
Tissue Location

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