BIRC5 Antibody

The BIRC5 Antibody from Abbiotec is a Rabbit Polyclonal antibody to API4, EPR-1, Baculoviral IAP Repeat Containing 5, BIRC5. This antibody recognizes Porcine, Canine, Bovine, Human antigen. The BIRC5 Antibody has been validated for the following applications: Immunohistochemistry, Western Blot, ELISA. BIRC5 (Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor suvivin) is a component of the chromosomal passenger complex (CPC), a key regulator of mitosis that functions at the centromere to ensure correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. With RAN, survivin forms a scaffold for mitotic spindle formation to deliver the RAN effector TPX2 to microtubules. Survivin plsys a role in neoplasia. It inhibits caspase-3 and caspase-7, blocking a default induction of apoptosis in G2/M phase. It is expressed in fetal kidney, liver, lung, brain, adenocarcinomas, lymphomas, renal cell carcinoma cell lines

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Canine, Bovine, Pig
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BIRC5
Supplier Abbiotec
Isotype Ig
Catalog Number 250560
Conjugation Unconjugated
Size 0.1 mg
Tissue Location

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