Bcl-2 Antibody

The Bcl-2 Antibody from Abbiotec is a Rabbit Polyclonal antibody to Bcl-2, BCL2, B-cell CLL/lymphoma 2, PPP1R50. This antibody recognizes Human, Mouse, Rat antigen. The Bcl-2 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1)

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Category Antibodies
Publication 0
Application ELISA, WB, IHC, IP
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Bcl-2
Supplier Abbiotec
Isotype Ig
Catalog Number 250555
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/bcl-2-antibody

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