Apaf-1 (N-term) Antibody

Abbiotec's Apaf-1 (N-term) Antibody is a Rabbit Polyclonal antibody. The Apaf-1 (N-term) Antibody was generated using CED4, apoptotic peptidase activating factor 1, Apaf-1, APAF1 as the antigen and it reacts with Mouse, Rat, Human. This antibody has been shown to work in applications such as: Immunohistochemistry, Western Blot, ELISA, Immunoprecipitation. Apoptosis protease activating factor-1 (Apaf-1) mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3) by forming oligomer upon binding with cytochrome c and dATP. Oligomeric Apaf-1 binds to pro-caspase 9 through their N-terminal CARD domains releasing mature caspase-9