Survivin Antibody

Abbiotec's Survivin Antibody is a Rabbit Polyclonal antibody. The Survivin Antibody was generated using EPR-1, Survivin, BIRC5, Baculoviral IAP Repeat Containing 5, API4 as the antigen and it reacts with Rat, Mouse, Human. This antibody has been shown to work in applications such as: Western Blot, Immunohistochemistry, ELISA. Apoptosis inhibitor survivin, also called baculoviral IAP repeat-containing protein 5 (BIRC5), is a component of the chromosomal passenger complex (CPC), a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. CPC is required for chromatin-induced microtubule tabilization and spindle assembly. Survivin interacts with tubulin and inhibits caspase-3 and caspase-7. Survivin is abundantly expressed in adenocarcinoma and high-grade lymphomas

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Survivin
Supplier Abbiotec
Isotype Ig
Catalog Number 250529
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/survivin-antibody

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