LDLR Antibody

The LDLR Antibody from Abbiotec is a Rabbit Polyclonal antibody to FHC, FH, low density lipoprotein receptor, LDLCQ2, LDLR. This antibody recognizes Human, Rat, Mouse antigen. The LDLR Antibody has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry. The Low-density lipoprotein receptor (LDLR) binds LDL, the major cholesterol-carrying lipoprotein of plasma, on the cell surface in clathrin-coated pits, followed by endocytosis. LDLR defects lead to familial hypercholesterolemia (FH), a common autosomal semi-dominant disease affecting 1 in 500 individuals and characterized by cholesterol deposit in the skin, tendons, and coronary arteries (atherosclerosis). LDLR acts as a receptor for the HIV-1 Tat protein in neurons and mediates its internalization

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human LDLR
Supplier Abbiotec
Isotype Ig
Catalog Number 250514
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/ldlr-antibody

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