Glutamate Decarboxylase Antibody

The Glutamate Decarboxylase Antibody from Abbiotec is a Rabbit Polyclonal antibody to glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), GAD65, GAD2, Glutamate decarboxylase. This antibody recognizes Human, Rat, Mouse antigen. The Glutamate Decarboxylase Antibody has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry. GAD65, an autoantigen in type I diabetes, is transiently activated in response to the demand for extra GABA in neurotransmission, and cycles between an active holo form and an inactive apo form. An inherently mobile catalytic loop promotes a side reaction that results in cofactor release and GAD65 autoactivation

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human glutamate decarboxylase
Supplier Abbiotec
Isotype Ig
Catalog Number 250501
Conjugation Unconjugated
Size 0.1 mg
Tissue Location

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