Cyclin D1 Antibody

The Cyclin D1 Antibody from Abbiotec is a Rabbit Polyclonal antibody to Bcl-1, Ccnd1, CD1, PRAD1, Cyclin D1. This antibody recognizes Rat, Mouse, Human, Canine antigen. The Cyclin D1 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, Western Blot. Cyclin-D1 (BCL-1) complexes with CDK4 and CDK6 serine/threonine protein kinases to impart substrate specificity. Cyclin-D1 is essential for G1/S phase transition. Following DNA damage, Cyclin-D1 is phosphorylated at Thr-286 by MAP kinases, leading to its FBXO31-mediated ubiquitination and subsequent degradation. Chromosomal aberrations of CCND1 lead to various neoplastic and proliferative disorders

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Mouse, Rat, Dog
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the central region of rodent Cyclin-D1
Supplier Abbiotec
Isotype Ig
Catalog Number 250491
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/cyclin-d1-antibody

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