Connexin-43 Antibody

The Connexin-43 Antibody from Abbiotec is a Rabbit Polyclonal antibody to Connexin-43, gap junction protein, alpha 1, 43kDa, HSS, DFNB38, gjal, AVSD3, oddd, GJA1, CX43, HLHS1. This antibody recognizes Human, Rat, Mouse antigen. The Connexin-43 Antibody has been validated for the following applications: Immunohistochemistry, ELISA, Western Blot. Connexin-43 (Gap junction alpha-1 protein, GJA1) forms connexons at cell gap junctions through which materials of low MW diffuse from one cell to a neighboring cell. Connexin-43 has a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Connexons are composed of a hexamer of connexins. Connexin-43 is expressed in the heart and fetal cochlear. Defects in Connexin-43 are the cause of autosomal dominant oculodentodigital dysplasia (ODDD), a serious condition of cranofacial anomalies, ocular defects and sometimes deafness and cardiac abnormalities

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human connexin-43
Supplier Abbiotec
Isotype Ig
Catalog Number 250486
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/connexin-43-antibody

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