Collagen IV (Mouse) Antibody

Abbiotec's Collagen IV (Mouse) Antibody is a Rabbit Polyclonal antibody. The Collagen IV (Mouse) Antibody was generated using COL4A4, Collagen, type IV, alpha 4, Collagen Iv as the antigen and it reacts with Porcine, Rat, Mouse. This antibody has been shown to work in applications such as: Western Blot, Immunohistochemistry, ELISA. Type IV collagen is the major structural component of glomerular basement membranes forming a "chicken-wire" meshwork together with laminins, proteoglycans and entactin/nidogen. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. Defects in type IV collagen are a cause of Alport syndrome autosomal recessive (APSAR), characterized by glomerulonephritis, renal failure, sensorineural deafness and eye abnormalities. Defects in type IV collagen are also a cause of benign familial hematuria (BFH). The antibody is directed against rodent alpha 1 isoform

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Mouse, Rat, Pig
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse type IV collagen (isoform alpha 1)
Supplier Abbiotec
Isotype Ig
Catalog Number 250485
Conjugation Unconjugated
Size 0.1 mg
Tissue Location

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