B7-H4 Antibody

Abbiotec's B7-H4 Antibody is a Rabbit Polyclonal antibody. The B7-H4 Antibody was generated using Vtcn1, V-set domain containing T cell activation inhibitor 1, B7-H4, PRO1291, B7h.5, B7S1, VCTN1, B7H4, B7X as the antigen and it reacts with Human, Rat, Mouse. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, Western Blot. Immune costimulatory protein B7-H4 (B7-H4) is expressed on the surface of a variety of immune cells and functions as a negative regulator of T cell response. By arresting cell cycle, B7-H4 inhibits growth, cytokine secretion and cytotoxicity development. When expressed on the cell surface of tumor macrophages, B7-H4 plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. B7-H4 is also involved in promoting epithelial cell transformation. B7-H4 can be a predictive marker for renal cell carcinoma

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Category Antibodies
Publication 0
Application ELISA, IHC, WB
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of human B7-H4
Supplier Abbiotec
Isotype Ig
Catalog Number 250473
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/b7-h4-antibody

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