AIF Antibody

The AIF Antibody from Abbiotec is a Rabbit Polyclonal antibody to COXPD6, apoptosis-inducing factor, mitochondrion-associated, 1, Aifm1, Aif, PDCD8. This antibody recognizes Mouse, Rat, Human antigen. The AIF Antibody has been validated for the following applications: Immunoprecipitation, Western Blot, Immunohistochemistry, ELISA. Apoptosis-inducing factor (AIF) is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. It has been demonstrated that AIF causes DNA fragmentation and chromatin condensation, and induces the release of cytochrome c and caspase-9 from mitochondria. Release of AIF from mitochondria was shown to be prevented by over-expression of Bcl-2, a protein involved in mitochondrial permeability