ADAM-TS7 Antibody

Abbiotec's ADAM-TS7 Antibody is a Rabbit Polyclonal antibody. The ADAM-TS7 Antibody was generated using ADAMTS7, ADAMTS-7, ADAM metallopeptidase with thrombospondin type 1 motif, 7, ADAM-TS 7, ADAM-TS7 as the antigen and it reacts with Mouse, Rat, Human. This antibody has been shown to work in applications such as: Immunohistochemistry, ELISA, Western Blot. A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS7) is a metalloprotease that degrades COMP. ADAM-TS7 is up-regulated in articular cartilage and synovium from arthritis patients. The spacer domain and the thrombospondin type-1 domain are important for a tight interaction with the extracellular matrix. The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme

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Category Antibodies
Publication 0
Application ELISA, WB, IHC
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ADAM-TS7
Supplier Abbiotec
Isotype Ig
Catalog Number 250456
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/adam-ts7-antibody

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