Thrombin (5D10) Antibody

Abbiotec's Thrombin (5D10) Antibody is a Mouse monoclonal antibody (clone 5D10). The Thrombin (5D10) Antibody was generated using RPRGL2, coagulation factor II (thrombin), F2, THPH1, PT, Thrombin as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: Western Blot, ELISA. Thrombin is the active enzyme that splits fibrinogen into fibrin in final stage of blood coagulation. It is generated from its circulating inactive precursor, prothrombin, by the action of factor Xa aided by factor Va, phospholipid and calcium ions. Thrombin is a glycoprotein formed by a 6-kDa A chain linked by a disulfide bridge to a 31-kDa B chain which carries the serine protease catalytic site. This antibody binds to human thrombin and to complexes of human thrombin with the thrombin inhibitor hirudin. No cross-reaction is seen with prothrombin. Cross-reactivity with thrombin from other species has not been tested

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Category Antibodies
Publication 0
Application ELISA, WB
Host Mouse
Reactivity Human
Clonality Monoclonal
immunogen Thrombin isolated from activated human plasma and adsorbed onto aluminum hydroxide gel
Supplier Abbiotec
Isotype IgG1 kappa
Catalog Number 250340
Conjugation Unconjugated
Size 0.2 mg
Tissue Location http://www.abbiotec.com/antibodies/thrombin-5d10-antibody

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