PHM Antibody

Abbiotec's PHM Antibody is a Mouse monoclonal antibody. The PHM Antibody was generated using PHM as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: ELISA. Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome. This antibody binds human PHM and cross-reacts with PACAP (approximately 12%, incomplete non-parallel inhibition). This antibody does not cross-react with GLP-1, GLP-2, VIP or glucagon

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Category Antibodies
Publication 0
Application ELISA
Host Mouse
Reactivity Human
Clonality Monoclonal
immunogen Synthetic human peptide histidine-methionine coupled to carrier
Supplier Abbiotec
Isotype IgG2a kappa
Catalog Number 250230
Conjugation Unconjugated
Size 0.2 mg
Tissue Location

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