C1s (9) Antibody

Abbiotec's C1s (9) Antibody is a Mouse monoclonal antibody (clone 9). The C1s (9) Antibody was generated using C1S, Complement Component 1, S Subcomponent as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: ELISA. C1s proenzyme is a 79.8 kDa glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single-chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca-dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2. This antibody is specific for C1s proenzyme and activated free C1s

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Category Antibodies
Publication 0
Application ELISA
Host Mouse
Reactivity Human
Clonality Monoclonal
immunogen C1s proenzyme purified from human plasma
Supplier Abbiotec
Isotype IgG1 kappa
Catalog Number 250213
Conjugation Unconjugated
Size 0.2 mg
Tissue Location http://www.abbiotec.com/antibodies/c1s-9-antibody

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