C4 Complement Antibody

Abbiotec's C4 Complement Antibody is a Mouse monoclonal antibody (clone KT29). The C4 Complement Antibody was generated using CO4, CPAMD2, C4S, complement component 4A (Rodgers blood group), C4A2, C4A3, C4A, C4AD, RG, C4A4, C4A6, C4 as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: ELISA. The complement component C4 plays a central role in the activation of the classical pathway of the complement system. C4 is cleaved by activated C1 which removes the C4a anaphylatoxin from the alpha chain. The remaining active C4b fragment becomes a subunit of the C3 convertase (C4b2a) and the C5 convertase (C3bC4b2a) enzymes of the classical complement pathway. The C4a anaphylatoxin is a mediator of local inflammatory process. The C4A6 allotype is totally deficient in hemolytic activity. This antibody recognizes the human complement C4 in ELISA

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Category Antibodies
Publication 0
Application ELISA
Host Mouse
Reactivity Human
Clonality Monoclonal
immunogen Purified human complement C4 protein
Supplier Abbiotec
Isotype IgG1
Catalog Number 250123
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/c4-complement-antibody

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