Factor I Antibody

Abbiotec's Factor I Antibody is a Mouse monoclonal antibody (clone KT22). The Factor I Antibody was generated using IF, C3b-INA, FI, Complement factor I, CFI, KAF, Factor I, C3BINA, AHUS3 as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: ELISA. The complement factor I is responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. These protein cleavages inactivate complement components C3b, iC3b and C4b. Factor I consists of a heterodimer of a light and heavy chains linked by disulfide bonds. Factor I deficiencies (CFI) result in increasing risks for pyrogenic infections, such as hemolytic uraemic syndrome (HUS), an acute renal failure in childhood due to E. coli infection. This antibody recognizes human complement factor I in ELISA

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Category Antibodies
Publication 0
Application ELISA
Host Mouse
Reactivity Human
Clonality Monoclonal
immunogen Purified human complement factor I protein
Supplier Abbiotec
Isotype IgG2b
Catalog Number 250120
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/factor-i-antibody

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