Factor B Antibody

Abbiotec's Factor B Antibody is a Mouse monoclonal antibody (clone KT21). The Factor B Antibody was generated using CFAB, FB, AHUS4, H2-Bf, BF, GBG, Factor B, CFB, Complement factor B, PBF2, BFD, FBI12 as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: ELISA. The complement factor B is part of the alternate pathway of the complement system. Factor B is cleaved by factor D into two fragments, Ba and Bb, the latter being a serine protease that binds to complement component 3b (C3b) to generate the C3 or C5 convertase. Factor B is involved in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. Among the 15 variants of factor B gene, the variants His-9 and Gln-32 are associated with a reduced risk of age-related macular degeneration (ARMD). This antibody recognizes human complement factor B in indirect and sandwich ELISA

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Category Antibodies
Publication 0
Application ELISA
Host Mouse
Reactivity Human
Clonality Monoclonal
immunogen Purified human complement factor B protein
Supplier Abbiotec
Isotype IgG2b
Catalog Number 250119
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/factor-b-antibody

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