EGFR Isoform 3

Abbiotec's EGFR Isoform 3 is a Rabbit Polyclonal antibody. The EGFR Isoform 3 Antibody was generated using ERBB1, epidermal growth factor receptor, HER1, EGFR, ERBB, Mena, PIG61 as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: ELISA, Western Blot. Epidermal growth factor receptor (EGFR) is a receptor for EGF and for various members of the EGF family such as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. EGFR is involved in the control of cell growth and differentation. Binding of EGF to the receptor leads to dimerization, internalization of the EGF-receptor complex, induction of the tyrosine kinase activity, stimulation of cell DNA synthesis and cell proliferation. EGFR isoform 3 (sEGFR, p110) is a 110kDa isofrom consisting of the extracellular EGFR domain and a unique, truncated carboxy terminus region. EGFR isoform 3 is being investigated as a marker for epithelial ovarian cancer

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Category Antibodies
Publication 0
Application ELISA, WB
Host Rabbit
Reactivity Human
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encomassing a sequence within the C-term region of human EGFR isoform 3
Supplier Abbiotec
Isotype Ig
Catalog Number 200211
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/egfr-isoform-3

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