OCRL1 Antibody

The OCRL1 Antibody from Abbiotec is a Rabbit Polyclonal antibody to OCRL1, NPHL2, oculocerebrorenal syndrome of Lowe, LOCR, OCRL-1, OCRL, INPP5F. This antibody recognizes Mouse, Human antigen. The OCRL1 Antibody has been validated for the following applications: ELISA, Western Blot. Inositol polyphosphate 5-phosphatase (OCRL1) converts phosphatidylinositol 4,5-biphosphate to phosphatidylinositol 4-phosphate. The enzyme also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. The enzyme is involved in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Defects in OCRL1 are the cause of Lowe syndrome, a multisystem disorder affecting eyes, nervous system and kidney, and Dent disease type 2, a renal disease

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Category Antibodies
Publication 0
Application ELISA, WB
Host Rabbit
Reactivity Human, Mouse
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human OCRL1
Supplier Abbiotec
Isotype Ig
Catalog Number 200177
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/ocrl1-antibody

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