BRCA1 Antibody

Abbiotec's BRCA1 Antibody is a Rabbit Polyclonal antibody. The BRCA1 Antibody was generated using Breast Cancer 1, Early Onset, IRIS, BRCAI, PPP1R53, BROVCA1, BRCC1, PNCA4, PSCP, RNF53, BRCA1 as the antigen and it reacts with Mouse, Rat, Porcine, Non-Human Primate, Human. This antibody has been shown to work in applications such as: Western Blot, ELISA. Breast cancer type 1 susceptibility protein (BRCA1) plays a central role in DNA repair by facilitating cellular response to DNA repair. BRCA1 is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. BRCA1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BRCA1 are a cause of genetic susceptibility to breast and ovarian cancers

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Category Antibodies
Publication 0
Application ELISA, WB
Host Rabbit
Reactivity Human, Monkey, Mouse, Pig, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BRCA1
Supplier Abbiotec
Isotype Ig
Catalog Number 200160
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/brca1-antibody

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