PTEN Antibody

The PTEN Antibody from Abbiotec is a Rabbit Polyclonal antibody to TEP1, PTEN1, 10q23del, MHAM, DEC, GLM2, MMAC1, phosphatase and tensin homolog, BZS, PTEN. This antibody recognizes Mouse, Rat, Xenopus/Amphibian, Zebrafish/Fish, Human, Non-Human Primate antigen. The PTEN Antibody has been validated for the following applications: ELISA, Western Blot. PTEN (Phosphatase and tensin homolog) is a dual-specificity protein phosphatase, dephosphorylating tyrosine-, threonine- and serine-phosphorylated proteins. PTEN has also a lipid phosphatase activity that is critical for its tumor suppression function. PTEN antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. Defects in PTEN are the cause of numerous cancers such as in Cowden disease (breast, thyroid and skin cancer predisposition), Lhermitte-Duclos disease, and head and neck squamous cell carcinoma

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Category Antibodies
Publication 0
Application ELISA, WB
Host Rabbit
Reactivity Human, Mouse, Rat, Monkey, Xenopus, ZebraFish
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PTEN
Supplier Abbiotec
Isotype Ig
Catalog Number 200145
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/pten-antibody

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