PERK Antibody

The PERK Antibody from Abbiotec is a Rabbit Polyclonal antibody to PERK, Eukaryotic Translation Initiation Factor 2-alpha kinase 3, WRS, EIF2AK3, PEK. This antibody recognizes Mouse, Rat, Human antigen. The PERK Antibody has been validated for the following applications: Western Blot, ELISA. PERK, a Ser/Thr protein kinase, phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and to a rapid reduction of translational initiation and repression of global protein synthesis. PERK serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1. Defects in PERK are the cause of Wolcott-Rallison syndrome, an early-onset diabetes mellitus

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Category Antibodies
Publication 0
Application ELISA, WB
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PERK
Supplier Abbiotec
Isotype Ig
Catalog Number 200117
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/perk-antibody

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