SYVN1 Antibody

Abbiotec's SYVN1 Antibody is a Rabbit Polyclonal antibody. The SYVN1 Antibody was generated using DER3, SYVN1, Synovial Apoptosis Inhibitor 1, Synoviolin, HRD1 as the antigen and it reacts with Human, Mouse, Rat. This antibody has been shown to work in applications such as: Western Blot, ELISA. Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates subsequently promoting their degradation. For instance, SYVN1 protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. SYVN1 is up-regulated in synovial tissues from patients with rheumatoid arthritis

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Category Antibodies
Publication 0
Application ELISA, WB
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SYVN1
Supplier Abbiotec
Isotype Ig
Catalog Number 200108
Conjugation Unconjugated
Size 0.1 mg
Tissue Location http://www.abbiotec.com/antibodies/syvn1-antibody

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